In order to predict the internal void closing behavior in open die forging process, multiple scale modeling has been developed and applied. The huge size difference between ingot and inner void makes it almost impossible to simultaneously model the actual loading conditions and the void shape. Multiple scale modeling is designed to integrate macro- and micro- models effectively and efficiently. The void closing behavior was simulated at 39 different locations in a large ingot during upsetting and cogging. The correlation between the closing behavior and variables such as effective plastic strain and maximum compressive strain was studied in order to find an efficient measure for predicting the soundness of the forging.