Valves are one of the most important components of a pipeline system in a nuclear power plant, and it is important to ensure their structural safety under seismic loads. A crucial aspect of structural safety verification is the seismic qualification, and therefore, an optimal shape design and experimental seismic qualification is necessary in case the configuration of the valve parts needs to be modified and their performance needs to be improved. Recently, intensive numerical analyses have been performed before the experimental verification in order to determine the appropriate design variables that satisfy the performance requirements under seismic loads. In this study, static and dynamic numerical structural analyses of a 200A butterfly valve for a nuclear power plant were performed according to the KEPIC MFA. The result of static analysis considering an equivalent static load under SSE condition gave an applied stress of 135 MPa. In addition, the result of dynamic analysis gave an applied stress of 183 MPa, where the CQC method using response spectrums was taken into account. These values are under the allowable strength of the materials used for manufacturing the butterfly valve, and therefore, its structural safety satisfies the requirements of KEPIC MFA.