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Molecular Typing of Clinical Cryptococcus gattii Isolates in Korea
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  • Molecular Typing of Clinical Cryptococcus gattii Isolates in Korea
  • Molecular Typing of Clinical Cryptococcus gattii Isolates in Korea
저자명
Hwang. Soo-Myung
간행물명
Journal of bacteriology and virology : JBV
권/호정보
2012년|42권 2호|pp.152-155 (4 pages)
발행정보
대한미생물학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Cryptococcus gattii causes life-threatening yeast infection in the pulmonary and central nervous systems of humans and animals, and traditionally has been considered to restrict into the tropical and subtropical areas. Despite rare incidence of cryptococcosis caused by C. gattii in Korea, three strains of C. gattii isolated from cryptococcosis patients between 1993 and 2010 were identified. To determine the genetic diversity, 3 strains of C. gattii were typed using PCR fingerprinting with primer M13 and the restriction fragment length polymorphism (RFLP) of orotidine monophosphosphate pyrophosphorylase (URA5) gene. All isolates were identified as serotype B and $MAT{alpha}$ mating type. The molecular types of each strain, on the other hand, turned out to be distinct belonging to VGI, VGII or III types, respectively. Although the travel histories of the patients were not available, clinical C. gattii strains isolated in Korea may represent the diverse molecular types existing worldwide.