Much research has been recently accomplished for standardization in cloud computing. However, little research on standardization of data sharing and exchanging has been studied. Most of all, the corresponding standardization organization suggests no specific standardization items and reference model. This paper defines the current standardization problems and proposes a set of specific standardization items and a reference model for supporting the semantic interoperability. To achieve the goal of this paper, the overall standardization trend in cloud computing is first analyzed. Especially, this paper describes the status of standard development for addressing the semantic interoperability of data. This paper also defines the potential standardization items based on the concepts of standards in the data exchanging and management field, which are used for developing standards in various fields. Finally, the reference model is describe to show the relationships between items and overall semantic interoperability process. This paper can be used as a guideline for development of standards and also can facilitate standardization of cloud computing.