Recent rapidly growth in nanotechnolgies is promised novel benefits through the exploitation of their unique industrial and biomedical applications. In addition, the production amount of these nanomaterials and nanoproducts has increased, and thus their uncontrolled release into the environment is anticipated to grow dramatically in future. Therefore, nanowaste streams must be effectively managed for sustainable nanotechnology. However, the effectiveness and capability of the current systems to handle nanowastes are yet to be established. In this review, we investigated several key topics for new paradigm of nanowaste treatment, (i) global and domestic production of nanomaterials and nanoproducts, (ii) definition and key resources of nanowaste, (iii) current and developing treatment method for nanowaste, and (iv) regulations for nanomaterials and nanoproducts.