In this study, a more practical and simulation approach which can predict the mechanical properties of aluminum alloys is proposed. First, cooling rate, micro-structure, and mechanical properties of casting product were measured through casting experiment. The relation between cooling rate and SDAS decrease exponentially and the linearly decreasing relation exist between SDAS and mechanical properties. Then, the cooling rate was calculated by casting process simulation and the mechanical properties were predicted by using the relations that were derived through experiment. Experimentally measured mechanical properties and predicted values by simulation were in the range of relatively small difference. The mechanical properties of various Al alloys are expected to be predicted by the casting process simulation before actual casting.