Hydraulic fracturing is used as a method for promoting the fluid flow in the rock and, in the energy field such as geothermal development and the development of sales gas, many studies has been actively conducted. In many cases, hydraulic fracturing is not performed in isotropic rock and especially in the case of sedimentary rocks, hydraulic fracturing is conducted in the transverse isotropic rock. The direction of the crack growth on hydraulic fracturing does not necessarily coincides with the direction of maximum principal stress in the transverse isotropic rock. Therefore, in this study, bonded particle model with hydro-mechanical coupling analysis was adopted for analyzing the characteristics of hydraulic fracturing in transverse isotropic rock. In addition, experiments of hydraulic fracturing were conducted in laboratory-scale to verify the validity of numerical analysis. In this study, the crack growth and crack patterns showed significant differences depending on the viscosity of injection fluid, the angle of bedding plane and the influence of anisotropy. In the case of transverse isotropic model, the shear crack growth due to hydraulic fracturing appeared prominently.