Since a slight malfunction of control systems in a nuclear power plant may cause huge catastrophes, such control systems usually have multiple redundancy and reliable features, and their reliability and availability should be analyzed and verified thoroughly. This paper performed the reliability analysis of the SPLC (Safety Programmable Logic Controller) that is under developed as the control systems for the next generation nuclear power plant. One of the key features of SPLC is that it has multiple redundancy modes as faults happen, which means the reliability analysis for one fixed redundant model is not enough to analyze the reliability of SPLC. With considering this reconfigurable concept, FTA (Fault Tree Analysis) was used to capture fault-relationship among sub-modules. The analysis results show that MTTF (Mean Time to Fault) of SPLC is 45,080 hours, which is a about 4.5 times longer than the regulation, 10,000 hours.