Objectives : The objective of this study is to investigate the influencing factors of turnover intention in dental hygienists and to find the management of manpower by path analysis. Methods : The influencing factors included working environment, external factors, and job satisfaction. Data were analyzed by SPSS 18.0 and AMOS 20.0. Results : Older and married persons were satisfied with their jobs. Turnover intention was higher in the single and more experienced persons. Job satisfaction and working environment factors were closely related with each other. Conclusions : Job satisfaction and working environment factors were closely related with each other. In order to reduce turnover intention, it is very important to enhance the work performance and self-esteem toward job in the dental hygienists.