- 한국약용식물의 최종당화산물 생성저해활성 검색 (XI)
- ㆍ 저자명
- 최소진,김영숙,송유진,김주환,김진숙,Choi. So Jin,Kim. Young Sook,Song. Yoo Jin,Kim. Joo Hwan,Kim. Jin Sook
- ㆍ 간행물명
- 생약학회지
- ㆍ 권/호정보
- 2013년|44권 4호|pp.372-378 (7 pages)
- ㆍ 발행정보
- 한국생약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
In this study, the inhibitory effect on advanced glycation end products (AGEs) formation of 43 Korean herbal medicines has been evaluated. Among them, 16 Korean herbal medicines were showed to have significant effect ($IC_{50}$; <50 ${mu}g/ml$) compared to positive reference, aminoguandine ($IC_{50}$: $76.47{pm}4.81{mu}g/ml$). Especially, five herbal medicines, Rubus coreanus (leaves, $IC_{50}$: $4.49{pm}0.03{mu}g/ml$), Rubus coreanus (twigs, $IC_{50}$: $3.80{pm}0.34{mu}g/ml$), Ampleopsis brevipedunculata (stems, $IC_{50}$: $7.43{pm}0.09{mu}g/ml$), Lindera erythrocarpa (leave, $IC_{50}$: $8.14{pm}0.20{mu}g/ml$), and Lindera erythrocarpa (stems, $IC_{50}$: $3.69{pm}0.14{mu}g/ml$) showed more potent inhibitory activity (approximately 9-20 fold) than the positive control aminoguanidine.