Heating method using electric heater was used to reduce water content in fingernail clippings. Authors found that low water content is helpful to measure EPR signal of fingernail sample with enhanced variability. Generally, natural dehydration happens in normal room condition at least one month and needs much time for using in experiment. So, artificial heating method is applied in this study for time savings. Fingernail samples were tested to find effect of water content to the EPR signal on microwave power levels for dosimetry. Low water content in fingernail reduced variability of EPR signal and makes it possible to measure accurate EPR signal. It also made it possible to measure constant movement of EPR signals on several microwave power levels. Although this method was difficult to apply directly in fingernail/EPR dosimetry, we, authors, believe that this heating method would be useful to differentiate MIS2 and RIS which are generally located at the same g-factor and almost impossible to be identified with each other.