Quantification of road noise is a challenging issue in the development of tire noise since its transfer paths are complicated. In this paper, a simplified model to estimate the road noise is developed. Transfer path of the model is from wheel to interior. The method uses the wheel excitation force estimated throughout inverse method. In inversion procedure, the Tikhonov regularization method is used to reduce the inversion error. To estimate the wheel excitation force, the vibration of knuckle is measured and transfer function between knuckle and wheel center is also measured. The wheel excitation force is estimated by using the measured knuckle vibration and the inversed transfer function. Finally interior noise due to wheel force is estimated by multiplying wheel excitation force in the vibro-acoustic transfer function. This vibro-acoustic transfer function is obtained throughout measurement. The proposed method is validated by using cleat excitation method. Finally, it is applied to the estimation of interior noise of the vehicle with different types of tires during driving test.