This study was performed to analyze the effect of light quality of discharge lamp on growth and phytochemicals contents of lettuce (Lactuca sativa L. cv. Jeokchima) grown under metal halide (MH) lamp, high-pressure sodium (HPS) lamp, and xenon (XE) lamp in a plant factory. Cool-white fluorescent (FL) lamp was used as the control. Photoperiod, air temperature, relative humidity, $CO_2$ concentration, and photosynthetic photon flux (PPF) in a plant factory were 16/8 h (day/night), $22/18^{circ}C$, 70%, 400 ${mu}mol{cdot}mol^{-1}$, and 200 ${mu}mol{cdot}m^{-2}{cdot}s^{-1}$, respectively. MH lamp had the greatest fraction of blue light (400-500 nm) of 23.0%. However, HPS lamp had the lowest fraction of 4.7% for blue light and the greatest fraction of 38.0% for red light (600-700 nm). At 11 and 21 days after transplanting, leaf length, leaf width, leaf area, shoot fresh weight, and shoot dry weight of lettuce as affected by the light quality of the discharge lamp were significantly different. The leaf area of lettuce grown under HPS, MH, and XE lamp increased by 45.7%, 16.3%, and 9.5%, respectively, as compared to the control. These results were similar for shoot fresh weight. Growth characteristics of lettuce grown under HPS lamp increased since HPS lamp had more fraction of red light. However, growth of lettuce grown under MH and XE lamp decreased since they had more fraction of blue light. As compared to the control, the ascorbic acid in lettuce leaves grown under discharge lamp decreased. The greatest anthocyanins accumulation of 0.70 mg/100 g was found at MH treatment. Anthocyanins content in lettuce leaves grown under XL and HPS lamp were 79.3% and 8.6%, respectively, compared with the control. Growth and phytochemicals contents of lettuce were highly affected by the different spectral distribution of the discharge lamp. These results indicate that the combination of discharge lamp or LED lamp for enhancing the light quality of discharge lamps is required to increase the growth and phytochemicals accumulation of lettuce in controlled environment such as plant factory.