Purpose: The purpose of this study was to evaluate the effects of using standardized patients on nursing competence, communication skills, and learning satisfaction in health assessment. Method: This study was a nonequivalent control group non-synchronized post-test design. Study participants were recruited from third-year nursing students at a university. The data were analyzed using the SPSS/WIN 18.0 program. Results: The mean scores of nursing competence and communication skills were significantly higher in the experimental group than the control group. However, the two groups were not statistically different in learning satisfaction. Conclusion: The findings suggest that the use of standardized patients compared to the traditional method is an effective educational method for health assessment in nursing competence and communication skills. Therefore, it is necessary to develop various scenarios and apply standardized patients for health assessment. In addition, further research is required to evaluate its effects.