Nowadays, optimum structural design techniques based on CSR have been developed and applied to the preliminary design stage focused on minimum weight and minimum construction cost of ship structure. Optimum structural design algorithm developed before could minimize weight and cost on fixed compartment arrangement. However, to develop more efficient design technique, a designer needs to combine optimized compartment arrangement with optimized ship structural design because compartment arrangement has a large effect on structural design according to the change of still water bending moment as a consequence of compartment arrangement change. In this study, automated algorithm for compartment arrangement of an oil tanker is developed to apply preliminary structural design. The usefulness of developed algorithm is verified with Aframax oil tanker constructed by STX shipbuilding Co.Ltd..