This study was performed to find out the knowledge and attitude of smoking, and smoking cessation recommendation among nursing students. The data were collected from 529 nursing students being at three colleges in Gwangju city through structured questionnaire from 1 to 30 October 2012. In results, the smoking cessation recommendation showed statistically significant differences in grading, residence, subjective health perception, recognition about smoking, present smoking, assessment experience of smoking history, experience of smoking cessation recommendations, and participation intention of smoking cessation intervention education. The smoking cessation recommendation had correlated with smoking knowledge and smoking attitude. In multiple regression analysis, the participation intention of smoking cessation intervention education, the attitude and knowledge of smoking, and experience of smoking cessation recommendation were significant factors of the smoking cessation recommendation explaining 15.5% of the variables. To enhance recommendations of smoking cessation for patients, there are necessary to enforce smoking cessation intervention program for nursing students and increase the experience of smoking cessation intervention recommendation of nursing students in clinical practice.