In this study, the impact loads on tank walls by sloshing phenomena and on a tall structure in a three-dimensional rectangular tank were predicted using multiphase flow simulations. The solver was based on the CIP/CCUP (Constraint interpolation CIP/CIP combined unified procedure) method, and the THINC-WLIC (Tangent hyperbola for interface capturing-weighted line interface calculation) scheme was used to capture the air-water interface. For the convection terms of the Navier-Stokes equations, the USCIP (Unsplit semi-lagrangian CIP) method was adopted. The results of simulations were compared with those of experiments. Overall, the comparisons were reasonably good.