With more and more high-rise building being constructed in recent decades, bluff body flow with high Reynolds number and large scale dimensions has become an important topic in theoretical researches and engineering applications. In view of mechanics, the key problems in such flow are high Reynolds number turbulence and fluid-solid interaction. Aiming at such problems, a parallel fluid-structure interaction method based on socket parallel architecture was established and combined with the methods and models of large eddy simulation developed by authors recently. The new method is validated by the full two-way FSI simulations of 1:375 CAARC building model with Re = 70000 and a full scale Taipei101 high-rise building with Re = 1e8, The results obtained show that the proposed method and models is potential to perform high-Reynolds number LES and high-efficiency two-way coupling between detailed fluid dynamics computing and solid structure dynamics computing so that the detailed wind induced responses for high-rise buildings can be resolved practically.