By using the radio propagation prediction of Rec. ITU-R P.1546, geographic information system, and S-I plane, we presented the methodology of interference analysis based on the minimum coupling loss, and also suggested the local coordinate system for calculating azimuth and elevation angles between the victim receiver and the interferer for an arbitrary antenna pattern. To check the presented algorithm, the map with the land-sea mixed area was taken for the given area of $80{ imes}60[km^2]$ as real geography information. Field strength, path profile, and protection ratio with maximum allowable interference level have been illustrated for radar and fixed wireless system for the assumed frequency. In addition interference power of the victim receiver was calculated asa function of azimuth and elevation angles of the interferer. The developed methodology of interference analysis in the VHF and UHF bands can be actually applied to assess interoperability as well as compatibility in the civil or military applications.