- 지출환(枳朮丸) Extract가 깨어있는 흰쥐의 위 수축력에 미치는 영향
- ㆍ 저자명
- 강경,윤상협,Kang. Kyung,Yoon. Sang-Hyub
- ㆍ 간행물명
- 대한한방내과학회지
- ㆍ 권/호정보
- 2013년|34권 2호|pp.147-154 (8 pages)
- ㆍ 발행정보
- 대한한방내과학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Objectives : The aims of this study was to find out whether Jichul-hwan (JCH) extract has an effect on gastric contractility in conscious rats by using a force transducer implanted in the body of the stomach. Methods : The force transducer (model: F-081S, Starmedical, JAPAN) was implanted to the exterior wall of the stomach body in rats. The gastric contractility was measured 30 minutes before and after administration of JCH (110.1 mg/kg). The control group was administrated with normal saline instead of JCH to compare the effect of JCH. The gastric contractility of the control group (normal saline: NS) was also measured 30 minutes before and after administration of NS. Results : The ratio of gastric contractility between before and after medication by JCH was $1.707{pm}0.731$, and with NS was $0.701{pm}0.541$. The gastric motility increased by JCH was significantly higher than NS. Conclusions : JCH extract increases gastric contractility in conscious rats. We could expect that this drug would be effective in the treatment of functional dyspepsia or post-surgical gastroparesis.