Reliability of a pin puller was predicted by Monte Carlo simulation. The prediction method is based on the stress-strength interference model that failure occurs if the stress exceeds the strength. In this study, the strength is considered as the energy delivered by combustion of pyrotechnics to retreat the pin to a predetermined position, whereas the stress is regarded as the energy required to resist the pin movement. The former mainly depends on the amount of pyrotechnic charge and the latter is governed by several friction forces and the energy dissipation within locking mechanism. Both the variables of stress and strength were computed using an analytical performance model. The method presented here, not depending upon a large number of test item, can be applicable to predict the reliability of other kinds of pyrotechnic devices.