Objectives : The purpose of this study was to examine the correlation between the professionalism and job satisfaction of clinical dental hygienists. Methods : The subjects were 310 dental hygienists in private and group practiced dental clinics. A self-reported questionnaire was conducted from December, 2012 to February, 2013. Data were analyzed using SPSS WIN 12.0. Results : Dental hygienists revealed the highest score in a sense of calling (3.41) and the lowest score in professionalism (2.85). They showed the highest score in the relationship with dentists (3.56) and the lowest score in pay (2.83). Highly educated and aged dental hygienists wanted to get more clinical career as professionalist. So there was a very significant positive correlation between professionalism and job satisfaction. Conclusions : Dental hygienists showed job satisfaction. Therefore it is important to develop the linking system of professionalsim and human resources development program.