In this paper, when the pulses propagate on a uniform microstrip line, the distortion of pulse signal caused by dispersion is investigated in time domain. We analyzed dispersion characteristics according to dielectric constant and structure of transmission line, and compared propagating characteristics for square and gaussian pulse according to pulse width, pulse amplitude, and propagation velocity. The results of this paper are compatible to the trade-off determination of relative permittivity, substrate height, strip width and pulse width of signal pulse when a design of MIC and MMIC is necessary.