This study is experimentally performed for using the oyster shell as a desiccant in the fluidized bed with bundle of heating pipe. The test material is oyster shell from fishery wastes which can use without costs. The main parameters of experiment are inlet air temperature, velocity of inlet air and heat flux of heating pipes. Also the geometry of heating pipe is treated as important parameter. From this study, the effect of inlet air temperature and input heat flux have much affect to increase the heat and mass transfer. On the other hand, the effect of inlet air velocity has less affect to increase the heat and mass transfer. And it is clarified that the oyster shell has sufficient probability for using as a desiccant in air-conditioning system.