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FINITE ELEMENT MODEL TO STUDY CALCIUM DIFFUSION IN A NEURON CELL INVOLVING JRYR, JSERCA AND JLEAK
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  • FINITE ELEMENT MODEL TO STUDY CALCIUM DIFFUSION IN A NEURON CELL INVOLVING JRYR, JSERCA AND JLEAK
  • FINITE ELEMENT MODEL TO STUDY CALCIUM DIFFUSION IN A NEURON CELL INVOLVING JRYR, JSERCA AND JLEAK
저자명
Yripathi. Amrita,Adlakha. Neeru
간행물명
Journal of applied mathematics & informatics
권/호정보
2013년|31권 5호|pp.695-709 (15 pages)
발행정보
한국전산응용수학회
파일정보
정기간행물|ENG|
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기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Calcium is well known role for signal transduction in a neuron cell. Various processes and parameters modulate the intracellular calcium signaling process. A number of experimental and theoretical attempts are reported in the literature for study of calcium signaling in neuron cells. But still the role of various processes, components and parameters involved in calcium signaling is still not well understood. In this paper an attempt has been made to develop two dimensional finite element model to study calcium diffusion in neuron cells. The JRyR, JSERCA and JLeak, the exogenous buffers like EGTA and BAPTA, and diffusion coefficients have been incorporated in the model. Appropriate boundary conditions have been framed. Triangular ring elements have been employed to discretized the region. The effect of these parameters on calcium diffusion has been studied with the help of numerical results.