In high-speed vehicle, selection of fuel, configuration of components and cooling system are required to solve the heating issue by aerodynamic heating and inner combustion process. This subsystem consists of fuel tank, supply pump, various control valve, heat exchanger, including reactor, connecting line, adiabatic structures and insulations. In this paper, applicable fuel property is considered at flight characteristic of hypersonic vehicles. In this regard, current state of fuel/cooling system technology is identified.