The purpose of this study is a chronic liver disease that affects the drinking behavior is to identify the factors. The subjects of the study was diagnosed with chronic liver disease outpatient visit were studied in 120 patients. The collected data were analyzed by using SPSS WIN 18.0. Drinking behavior of chronic liver disease to determine the factors influencing the results of the multiple regression analysis, the regression model was found to be significant(F=8.58, p<.001), drinking behavior of chronic liver disease a major contributor to the drinking habits(${eta}$ = -.29, p = .004)was found in, followed by drinking motives(${eta}$ = .20, p = .044), drinking refusal self-efficacy(${eta}$ = -.17, p = .037), after which the diagnosis of the disease(${eta}$ = .15, p = .041), respectively. These variables showed explanatory power of 44.1%. Drinking behavior is a serious health problem in patients with chronic liver disease. The factors that influence drinking behavior by considering the management of chronic liver disease drinking continued to provide information and education is needed abstinence.