Camera for QUasars in EArly uNiverse (CQUEAN) is an optical CCD camera system made by Center for Exploration of the Origin of the Universe (CEOU). CQUEAN is developed for follow-up observation of red sources such as high-redshift quasar candidates ($z{geq}5$), gamma-ray bursts (GRB), brown dwarfs and young stellar objects. The CQUEAN is composed of a science camera with deep-depletion CCD chip which is sensitive at around $1{mu}m$, a set of custom-made wide-band filters for detection of quasar candidates at z~5, and a guide camera. A focal reducer was developed to secure $4.8^{prime}{ imes}4.8^{prime}$ field of view, and an in-house user software for efficient data acquisition. CQUEAN was attached to 2.1m Otto Struve Telescope in McDonald Observatory, USA, in August 2010. About 1000 quasar candidates including 3 confirmed with follow-up spectroscopy, have been observed so far, and many high-z galaxy cluster candidates, GRBs and supernovae were also observed. And monitoring of HBC 722, a young stellar object, is under way since 2011. Further enhancement of CQUEAN including the introduction of narrow-band filters is planned.