Purpose: This study was to explore the differences of Korean and Chinese university students for developing smoking cessation program. Methods: The Data was collected from 120 Korean, 103 Chinese undergraduate students by using structured questionnaire from 1st April to 31st July, 2012. Results: The necessity of smoking cessation training was found that there were differences between two groups, showing that 60% of Korean university students and 35% of Chinese university studying in Korea were award of the necessity. For the score of smoking knowledge, there were significant differences between two groups, showing 13.60 from Korean students and 14.63 from Chinese students, but there were no differences towards Smoking attitude, self-efficacy related to smoking cessation, and Nicotine dependency. On the other hand, there were no significant differences toward demand of overall smoking cessation training between Korean and Chinese students, showing 43.4 and 45.1 scores in each group. Conclusion: The results of this study would be helpful to develop smoking cessation programs and health promotion strategies for both Korean and Chinese university students.