Purpose: This survey was to investigate the differences in smartphone addiction symptoms by the level of addiction among college students in S. Korea. Methods: Two hundred and thirteen university students survey data was collected from December 5th to 9th of 2011 using Smartphone Addiction Scale. 25.3% (n=54) of total respondents were categorized as highly addicted and 28.17% (n=60) were as non-addicted group. Results: There were significant differences in total addiction symptom scores, daily life disorders, loss of self control, pathological concentration, and compulsive symptoms between two groups. There were significantly differences in total addiction symptoms, daily life disorders, loss of self control, pathological concentration, and compulsive symptoms between two groups. Highly addicted group were significantly higher in total addiction symptom scores (3.26 times), daily life disorders (4.96 times), loss of self control (3.07 times), pathological concentration (3.07 times), and compulsive symptoms (2.86 times) compared to non-addicted one. Highly addicted group had significantly higher daily usages of smartphone and were more satisfied with smartphone than non-addicted group. The purpose to use was related to academic works rather than games or entertainment. However satisfaction on academic achievement was very low. Conclusion: The smartphone addicted symptoms related to academic works were significantly high in highly addicted college students so that it disturbed their daily life and psycho-social health in general. It is clear that the highly addicted college students need urgent distinctive interventions such as creative academic guides.