In this study, a series of dynamic centrifuge tests were performed for a soil-foundation-structural interaction system in dry sand with various embedded depths and superstructure conditions. Sinusoidal wave, sweep wave and real earthquake were used as input motion with various input acceleration and frequencies. Based on the results, a natural period and an earthquake load for soil-structure interaction system were evaluated by comparing the free-field and foundation accelerations. The natural period of free field is longer than that of the soil-foundation-structure system. In addition, it is confirmed that the earthquake load for soil-foundation-structure system is smaller than that of free-field in short period region. In contrast, the earthquake load for soil-foundation-structure interaction system is larger than that of free-field in long period region. Therefore, the current seismic design method, applying seismic loading of free-field to foundation, could overly underestimate seismic load and cause unsafe design for long period structures, such as high-rise buildings.