The growth of micro bubble has been simulated under the variation of ambient pressure. The Rayleigh-Plesset equation governs the dynamic growth and collapse of a bubble according to pressure and temperature conditions. The Rayleigh-Plesset equation was solved by 4th-order Runge-Kutta method for wide range of pressure variations. As numerical parameters, the pressure difference between initial and final pressures, and the temporal pressure gradient are changed. The results show that the pressure difference has little effect on the growth rate of the micro bubble in the inertia controlled growth region. On the other hand, the growth rate increases linearly with the increase of the pressure gradient.