Liquid lubricants are widely used to reduce the friction and wear of mechanical components. In this research, silicone oil and canola oil were used to investigate the effectiveness of vapor phase lubrication in the lubrication of aluminum and copper. Specifically, the aim was to assess the friction reduction characteristics of a high molecular weight lubricant by vapor phase lubrication. Friction experiments were performed using a specially built test chamber for vapor phase lubrication. The silicone oil and canola oil were heated to produce the vapor phase. Then, the vapor phase lubricant was injected into the test chamber. Aluminum and copper plates were slid against stainless steel balls in the friction tests. The results of the friction experiments showed that the vapor phase lubrication using a high molecular weight lubricant was effective in reducing the friction of aluminum and copper. It was also observed that the friction coefficient of the silicone oil vapor phase lubrication temporally increased due to decomposition of the oil. The vapor phase technique should be optimized based on the type and characteristics of the lubricant. The results of this work demonstrate the possibility of vapor phase lubrication for the friction reduction of metals.