- 우라자미드 정의 유해시약 대체 시험법의 개발
- ㆍ 저자명
- 이유림,김현지,서나래,김경호,Lee. Yoo Rim,Kim. Hyun Ji,Seo. Narae,Kim. Kyeong Ho
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 2014년|58권 2호|pp.125-128 (4 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
We developed an alternative assay method without hazardous reagent of chloroform for urazamide tablets in Korean Pharmaceutical Codex. The HPLC analytical method was validated by system suitability, linearity, precision, accuracy and robustness. The linearity of the calibration curves in the desired concentration range is good ($r^2$ >0.999). Precision was obtained less than RSD 1.17%. Accuracy was obtained with recoveries in range of 98.12% and 99.47%. The developed assay could be expected to become valuable tools for revising the Korean Pharmaceutical Codex.