Many industrial processes such as continuous stirred tank reactors(CSTRs), desalination plant, distillation columns, pH neutralization processes and so on exhibit highly nonlinear characteristic and time-varying behavior during operation. The control of such processes has been challenging to control engineers. Hence, a variety of forms of PID controllers and their tuning rules for industrial processes have been developed to guarantee the best performance. In this paper, a scheme that designs the practical PID controller with an anti-windup strategy incorporating with an evolutionary algorithm(EA) is presented for the concentration control of a nonisothermal CSTR. EA is used to tune the parameters of the overall PID control process with anti-windup by minimizing the integral of absolute error(IAE). Simulation works for reference tracking and disturbance rejecting performances and robustness to parameter changes show the feasibility of using the proposed method.