The purpose of this study was to identify the relation of appearance satisfaction, self-efficacy, and school life adaptation of adolescent and to provide basic data for improving appearance satisfaction, self-efficacy, and school life adaptation. The participants were 199 second grade stndents of three high schools in C city. Data were collected from September 21 to September 25, 2012 and by a structured questionnaire. The collected data were analyzed by t-test, ANOVA, Pearson correlation coefficient using the SPSS/WIN(ver.20.0). The score of appearance satisfaction, self-efficacy, and school life adaptation were relatively moderate. The study showed significant differences in the score of appearance satisfaction and school life adaptation according to gender and economic status. Appearance satisfaction and self-efficacy had significantly positive correlations-with school life adaptation. Therefore, these results should be considered when developing intervention programs for improving school life adaptation, self-efficacy, and school life adaptation of adolescent.