This research aimed to grasp the optimal location for two-outrigger system in high-rise building by using MIDAS-Gen. In this study, the main variables of structural analysis research were the outrigger location, the outrigger spacing and the stiffness of primary structural members such as outrigger systems, exterior columns connected in outrigger system, shear walls and frames. For the purpose of investigating the optimal position for two-outrigger system in tall building, we compared and examined the lateral displacement in top floor of 80 stories high-rise building. In the results of this analysis research, it is showed that the outrigger location, the outrigger spacing and the stiffness of primary structural members such as outrigger systems, exterior columns connected in outrigger system and shear wall had an impact on the optimal location of two-outrigger system. Furthermore, it is indicated that the study results can provide assistance in getting the structural design data for searching the optimal location of two-outrigger system in tall building.