Objectives : The purpose of this study is to investigate the influencing factors on attitude, satisfaction and stress in clinical practice in dental hygiene students. Methods : The subjects were 304 dental hygiene students living in Suwon. The data were collected from 2012 to 2013 by a self-reported questionnaire. The data were analyzed using SPSS. Results : Clinical practice showed good results in attitude, satisfaction and stress than that in the classroom. Satisfaction in the classroom practice was proportional to clinical practice. The contents, learning management system, and the assessment tool in the classroom influenced on the dental clinical practice. As the dental clinic practice became stressful, the students tended to have negative feelings for the practice. Conclusions : In order to provide the best clinical practice contents to the dental hygiene students, it is important to prepare the best combination of the contents, learning management system, and the assessment tool in the classroom.