A study is analyzed on the design factor of center-body diffuser and performed on conceptual design of center-body diffuser with computational fluid dynamic. The flow field of center-body diffuser is calculated using axisymmetric two-dimensional Navier-Stokes equation with $k-{epsilon}$ turbulencemodel. The center-body diffuser is compared with second throat exhaust diffuser in terms of starting pressure, the degree of vacuum pressure and the design factors. The counter flow jet on cone-tip of the center-body is applied for thermal protection system in the center-body diffuser.