The purpose of this study was investigated optimal exposure condition in digital magnification mammography to decrease radiation dose and increase image quality of the examinee. Auto mode, the average glandular dose is higher than the manual mode. Average glandular dose and image quality were many differences on between grid and air gap technique in auto mode. However, Average glandular dose and signal-to-noise ratio were not different on between grid and air gap technique in manual mode. The signal-to-noise ratio was increased when using the air-gap technique in both mode. According to result, air gap technique may reduce average glandular dose and increase signal-to-noise ratio in digital magnification mammography.