Using complex sample design, this article analyzes the difference between sex and age groups of mental health, physical activity, suffering lifestyle diseases, drinking, and smoking using the fifth Korea national health and nutrition examination survey data (2011-2012), and then analyzes the effect of mental health, physical activity, suffering lifestyle diseases, drinking, and smoking on EQ-5D, a measure of health-related quality of life. The results show that mental health, physical activity, suffering lifestyle diseases, drinking and smoking are statistically different among gender and age groups, and that age group, education level, suffering diabetes, recognizing stress, thinking suicide are statistically influential on EQ-5D.