Optimal Distributed Generation (DG) output and reconfiguration are among the well accepted approach to reduce power loss in a distribution network. In the past, most of the researchers employed optimal DG output and reconfiguration separately. In this work, a simultaneous DG output and reconfiguration analysis is proposed to maximize power loss reduction. The impact of the separated analysis and simultaneous analysis are investigated. The test result on the 33 bus distribution network with 3 units of DG operated in PV mode showed the simultaneous analysis gave the lowest power loss (global optimal) and faster results compared to other combined methods. All the analyses for optimizing the DG as well as reconfiguration are used the Artificial Bee Colony Optimization technique.