Robustness and controllability are the key factors in internal combustion engine commercialization. This study focuses on the combustion strategy to commercialize the low temperature diesel combustion technology. Various LTC combustion methods such as PPCI, MK and highly diluted mixing controlled LTC were conducted on 6.0L heavy duty diesel engine. To find the best feasible LTC strategy, emission level, fuel consumption and combustion safety during the combustion mode change were considered. Experiments were carried out under various engine operating conditions; engine speed & load, EGR level, injection timing. Finally, this study suggests realizable LTC combustion strategy; moderate EGR level and slight early injection are possible to considerably lower PM, NOx emission and expand LTC operating range up to 50% load without CO and HC emission.