"Hyegukji (惠局志)" was written in 1719 by Gwanguibing (姜渭聘), who was Hyeminseo (惠民署) medical bureaucrat. This book contains rare data such "sigrye (式例)" which shows Hyeminseo medical bureaucrat living during the 18th century. This is unique data related to Hyeminseo in detail and affluence. The purpose of this study is to introduce and analyze the formation and contents of "Hyegukji". Also content comparison between "Hyegukji" and law books as "Daejeon tongpyen (大典通編)" shows changes in medical bureaucracy of the Joseon Dynasty.