Purpose : The purpose of this research was to determine the effects of nap between therapeutic interventions on motor learning in patients with stroke. Method : Thirty stroke patients with hemiplegia were participated in this study. After the screening by questionnaire about nap time, the patients were assigned to nap or non-nap group. Therapeutic interventions for 30 min were provided two times per day for 5 days per week and the serial reaction time tasks were conducted 2 times before and after a nap per day for 3 days per week. Between the therapeutic interventions, a nap for 60~120 minutes was allowed to the nap group while non-nap group was not. Intervention programs were carried out during the total 15-day. Result : Compared with the non-nap group, the reaction-precision level of nap group was increased (p<.05) for the non-affected upper extremity in the serial reaction time tasks. Conclusion : This study demonstrated that nap between therapeutic interventions has positive effects on motor learning in patients with stroke.