It is an element certainly required for the cost reduction of a company that forward and reverse logistics chain are unified and constitutes a resource closed-loop supply chain (CLSC). In this study, the inventory control which unifies inventory of distribution centers (DCs) of forward logistics and processing center of reverse logistics in the CLSC environment is proposed. The inventory system model for newly-constructed CLSC considers the JIT(Just-In-Time) delivery from the processing center to the manufacturer, including the making of decisions on whether to wait for the arrival of end-of-life products or to back-order necessary products for manufacturer when the supply of end-of-life products at the processing center via the returning center is insufficient for the demands of the manufacturers. The validity of the proposed model was verified using the genetic algorithm (GA). In order that a parameter might investigate the effect which it has on a solution, the simulation was carried out for priGA(priority-based GA) on three kinds of parameter conditions. Moreover, mhGA(modified hybrid GA) to which a parameter is adjusted for every Study on Reducing Logistics Costs and Inventory Control System according to facilities integration in the Closed-Loop Supply Chain Environment generation, the simulation was carried out to a four-kind numerical example.