The purpose of this research is to find the impact of multicultural awareness of pre-service secondary teachers on multicultural efficacy. Specific content of the study for achieving this purpose is as follows: First, the correlation between multicultural awareness of pre-service secondary teachers and multicultural efficacy was analyzed. Second, the effect relation between multicultural awareness of pre-service secondary teachers and multicultural efficacy was examined. As part of quantitative research, the method of study was a survey targeting 234 pre-service Secondary teachers who were sophomores, juniors and seniors at D University, P University and S University located in Busan. The study results earned from this process are as below: First, statistically significantly high positive correlation existed between multicultural awareness of pre-service secondary teachers and multicultural efficacy. The areas of acceptance, openness and respect, which are the sub-scale of multicultural awareness of pre-service secondary teachers, showed high positive correlations with all sub-scale of multicultural efficacy including general efficacy, efficacy in instructional function, efficacy in caring perspectives and efficacy in helping multicultural families. Second, the sub-scale of multicultural awareness that significantly affected general efficacy in the sub-scale of multicultural efficacy of pre-service secondary teachers was acceptance and respect. The sub-scale of multicultural awareness that significantly affected efficacy in instructional function was acceptance. The sub-scale of multicultural awareness that significantly affected efficacy in caring perspectives was acceptance and respect. The sub-scale of multicultural awareness that significantly affected efficacy in helping multicultural families was respect. It showed that openness in the sub-scale of multicultural awareness did not affect multicultural efficacy much.