The aim of the shaking table experiment is to verify the isolation effect of a storage liquid tank with multiple friction pendulum bearings. A 1:20 scale model of a real storage liquid tank that is widely used in the petroleum industry was examined by the shaking table test to compare its anchored base and isolated base. The seismic response of the tank was assessed by employing the time history input. The base acceleration, wave height and tank wall stress were used to evaluate the isolation effect. Finally, the influences of the bearing performance that characterizes the isolated tank, such as the friction force and residual displacement, were discussed.