The present study examined differences in children's behavior problems and peer interaction, and parental factors including self-esteem, depression and childrearing stress between atopic dermatitis(AD) and normal(non-AD) children in each gender, and analyzed the effects of the parental factors on the two variables of AD children. 165 AD and 1176 non-AD children of age 5 were selected from the 6th year data of the Panel Study on Korean Children. The results from t-test and multiple regression are as follows. First, only AD boys showed a higher level of behavior problems than non-AD boys, but peer interaction showed no difference between AD and non-AD groups. Compared with non-AD children’s parents, mothers of AD children showed a higher stress level and mothers of AD boys had a higher depression level. But there were no differences in maternal self-esteem and paternal factors between the groups. Second, AD boys’ behavior problems were related to maternal factors and paternal stress, and some characteristics of AD girls’ behavior problems were related with some parental variables. But peer interaction of AD children had no relation with parental factors. Third, behavior problems were influenced by maternal stress in AD boys and influenced by maternal depression and parental self-esteem in AD girls.