This study investigated the effects of virtual reality(VR) and augmented reality(AR) based guiding inquiry instruction(VR-AR-GII) on ‘solar and star’ in science of students with learning disabilities. 31 elementary students with LD participated in this study. They were assigned into two groups according to academic achievement in science. 15 students were assigned control group and were taught traditional intervention in science classes. 16 students were assigned experimental group and were taught VR-AR-GII. The collecting data was analysed by ANCOVA and Independent t-test. According to the results of the study, Experimental group was statistically significant more higher than control group on academic achievement in science, engagement in science classes, and attitude in science classes. This findings was showed that VR-AR-GII will be applied in science education for students with LD.